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A pain reliever used for pain in the lower back New research.
The study published online in the magazine Regional Anaesthesia & Pain Medicine showed that groups that were previously considered too young to develop the conditions were more than twice the risk of taking Gabapentin.
“Our results indicate a connection between Gabapentin recipe and dementia or cognitive impairment within 10 years,” said the research team in a press release.
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The drug is increasingly popular for the treatment of chronic pain, especially in neuropathic (nerve) pain, as the researchers found in a press release.
Gabapentin, who, according to Cleveland Clinic, is also used to control seizures, has a relatively low addiction potential compared to Cleveland Clinic Traditional opioids.
Gabapentin is increasingly popular with the treatment of chronic pain, especially in neuropathic (nerve pain), as experts found. (IStock)
Recent studies have triggered new concerns about the side effects, including a possible connection with neurodegenization.
Earlier results could not confirm a certain link, especially with regard to the question of whether Certain age groups are more susceptible.
In the most recent study, researchers collected data from Trinetx, a health research network that contains the electronic health records of 68 health organizations in the USA
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Investigation of anonymous records of adult patients examined the team groups that Gabapentin was prescribed for chronic lower prescriptions Back pain Between 2004 and 2024 it compared it to people who had not received the drug. There were a total of 26,414 people in each group.
The researchers took into account factors such as demographic data, at the same time existing diseases and the use of other pain relieving medication.
People between the ages of 18 and 64 who received Gabapentin developed more than twice as often a condition than those to whom the medication had not been prescribed. (IStock)
Patients who had received six or more Gabapentin recipes with dementia And 85% more often with the diagnosed MCI within 10 years after the initial pain diagnosis, the study showed.
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Under consideration of certain age groups, people between the ages of 18 and 64 who received the medication more than twice as often that the two conditions were the case as those that Gabapentin had not been prescribed.
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While there was no increased risk at 18 to 34 years, the goods prescribed the medicationThe risk of dementia has more than doubled in 35- to 49-year-olds (and the risk of MCI more than tripled).
The researchers observed a similar pattern for 50- to 64-year-olds.
In patients in whom six or more Gabapentin recipes received, 29% more often were diagnosed with dementia and 85% more often with MCI diagnosed with MCI within 10 years after the initial pain diagnosis, as the study stated. (IStock)
The risks rose with prescription frequency: Patients with 12 or more recipes developed 40% greater probability of developing dementia, and 65% more likely developed MCI than patients who were prescribed between three and eleven times.
“Our results indicate a connection between the Gabapentin recipe and dementia or cognitive impairment within 10 years.”
The study had some restrictions. Since this was an observation study, no fixed conclusions on the cause and effect can be drawn, according to the researchers.
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They also recognized that the study because it was retrospective could not take a dose or length of the Gabapentin use into account.
The results “support the need for close surveillance of adult patients who have prescribed Gabapentin to evaluate a potential cognitive decline,” added the researchers.
