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Experts believe that they have identified a chemical Connection in certain herbs This could help to mitigate or prevent Alzheimer’s disease – but before someone takes a run for the spice shelf, there are a few catches.
In a study published in the Journal Antioxidants at the beginning of this year, researchers from the SCRIPPS Research Institute identified a connection name Rosemary and sage.
In the case of neurodegenerative disorders, the connection could prove to be therapeutic, including Alzheimer’s disease, the experts concluded.
According to the study, the common household spice can affect the medication
Carnosic acid contains “striking antioxidants [and] Inhibitory properties, ”the researchers wrote in the results.
Scripps Research Postdoctoral Associate Piu Banerjee and the neurologist Dr. Stuart Lipton based in California spoke with Fox News Digital about the results.
Carnosic acid can be found in rosemary and sage that are popular kitchen clips. However, there are precautionary measures in relation to them. (IStock)
“In this study we observed that the administration of this drug on mice that were advanced Alzheimer’s-like disease The number of neurons as well as the number of synapses or connections between the brain cells significantly improved, ”said the team.
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The experts added: “It also reduced the inflammation caused by the current anti-amyloid antibody therapies. We have also observed an improvement in learning and memory of the mice that the medicine received.”
“From the results of our animal studies, we are carefully optimistic for their success in the clinical studies of humans.”
Banerjee and Lipton also noticed that carnosic acid is a “procrug”, which means that it is initially inactive – but as soon as it enters the body, it is activated by oxidative and inflammatory stress.
“It is aimed specifically against cells that are oxidative and anti -inflammatory without influencing them Healthy, normal brain cells“Banerjee said.
Using an acid in rosemary, scientists generated a new drug that reduced inflammation and improved connections to the brain cells in mice. Many more studies have to be carried out. (IStock)
“This continues to make a safe option for therapeutic agents.”
The experts agreed that carnosic acid could possibly improve the inflammation that generally appeared in most appearance Aging brains.
However, there are precautionary measures.
Courtney Kloske, director of scientific engagements at the Alzheimer’s Association based in Chicago, told FOX News Digital that studies are based on one Mouse model from Alzheimer Can be helpful, but are not conclusive.
There are inadequate clinical evidence to recommend Rosemary and sage as standard therapy.
“Models are important to help us understand the basic biology of the disease, but we need human studies in representative population groups so that ideas can be fully validated,” said Kloske.
“Therefore, it is fascinating knowledge, but more research is required to understand the effects and results of these compounds on people who with or life, or Danger for Alzheimer’s. “
Kocher and rosemary do not deliver the complete anti -inflammatory effects, Banerjee and Lipton.
Researchers are optimistic about future studies that affect the new drug and believe that it has the potential to help those suffering from Alzheimer’s disease. However, it is too early to know. (IStock)
“You cannot take sufficient herbs critically to achieve the same effect as Our new drug,“Banerjee said.
The researchers entered the study, some of which was financed by the National Institutes of Health, gave the researchers.
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Kloske advised to prevent “these herbs (or carnosic acid) at this time to prevent or treat Alzheimer’s or other cognitive impairments.”
Dr. Lee Murray, a neurologist in Jackson, Tennessee, repeated Kloske’s concerns.
The scientists found that cooking herbs do not bring the same benefit to anyone the medication does. (IStock)
“Before patients start to include rosemary and sage in Every dish you eatWe have to remember that these studies are pre -clinical, “Murray told Fox News Digital.
“There is currently not enough clinical evidence to recommend Rosemary and Sage as standard therapy for Alzheimer’s dementia.”
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Murray, however, said the data was “encouraging” and opens the door to an additional way for potential therapeutic agents.
Banerjee said she hope that “our drug will start Clinical studies soon.”
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She added: “If it turns out to be effective, it will be a big new medication for those who suffer from Alzheimer’s. From the results of our animal studies, we are carefully optimistic about his success in the clinical studies of human clinic.”
